By the Banger Labs Research Team · Updated June 2026
What is GHRP-2?
GHRP-2, also known as pralmorelin (developmental codes KP-102, GPA-748, WAY-GPA-748), is a synthetic peptide of the growth hormone-releasing peptide (GHRP) family with the sequence H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 (where D-2-Nal denotes D-2-naphthylalanine). It is classed as a hexapeptide (six amino-acid residues, molecular weight ~817.97) and was among the first synthetic growth hormone secretagogues described in the scientific literature. It is used in research settings as a tool compound for probing the growth hormone secretagogue / ghrelin-receptor system.
How GHRP-2 is studied
In published research, GHRP-2 acts as an agonist at the growth hormone secretagogue receptor type 1a (GHS-R1a), the same G-protein-coupled receptor bound by the endogenous peptide ghrelin, which is expressed in the anterior pituitary and hypothalamus. Receptor activation is associated in preclinical models with Gq/11–phospholipase C signaling and stimulation of growth hormone release from pituitary somatotrophs. Studies also report interactions with other signaling pathways, including opioid-receptor-linked effects observed in rodent models.
Research areas
- Studied in preclinical models as a growth hormone secretagogue acting via the GHS-R1a/ghrelin receptor
- Investigated in animal models of pain signaling (e.g., supraspinal antinociception involving opioid receptors in mice)
- Examined in rodent models of muscle proteolysis and catabolic/injury states (e.g., MuRF-1/MAFbx expression)
- Used as a pharmacological tool to probe ghrelin-receptor signaling and downstream second-messenger cascades
- Studied in endocrine research contexts as a probe of growth hormone axis physiology
These describe laboratory/preclinical research only. No therapeutic, medical, or efficacy claims are made.
GHRP-2 specifications
Handling & quality
GHRP-2 is held to a ≥ 99% HPLC purity standard with a Certificate of Analysis available per batch. Reconstitute with bacteriostatic water and store refrigerated; handle strictly for research. See reconstitution & storage.
Frequently asked questions
What is GHRP-2?
GHRP-2, also known as pralmorelin (developmental codes KP-102, GPA-748, WAY-GPA-748), is a synthetic peptide of the growth hormone-releasing peptide (GHRP) family with the sequence H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 (where D-2-Nal denotes D-2-naphthylalanine). It is classed as a hexapeptide (six amino-acid residues, molecular weight ~817.97) and was among the first synthetic growth hormone secretagogues described in the scientific literature. It is used in research settings as a tool compound for probing the growth hormone secretagogue / ghrelin-receptor system.
Is GHRP-2 research use only?
Yes. GHRP-2 is supplied strictly for laboratory research — not for human or veterinary use, and not as a drug, food, or supplement.
Does Banger Labs provide a COA for GHRP-2?
Yes — a Certificate of Analysis (HPLC purity + mass-spec identity) is available per batch on request. See the COA Library.
References
- Pralmorelin (GHRP-2) — structure, peptide class, developmental codes, and ghrelin/GHS-R agonist mechanism — Wikipedia
- Ghrelin receptor agonist, GHRP-2, produces antinociceptive effects at the supraspinal level via the opioid receptor in mice (Peptides, 2014) — PubMed (PMID 24607724)
- Ghrelin receptor agonist, GHRP-2, attenuates burn injury-induced MuRF-1 and MAFbx expression and muscle proteolysis in rats (Peptides, 2009) — PubMed (PMID 19577604)
- Pralmorelin — drug entity record (identity, class, GHS-R1a mechanism) — NCATS Inxight Drugs
Sources are provided for scientific reference and describe laboratory/preclinical research; they do not constitute medical advice or efficacy claims.
Shop GHRP-2 & related research peptides
By the Banger Labs Research Team. For research use only. Not for human or veterinary use. Not a drug, food, or cosmetic. Educational information, not medical advice.