By the Banger Labs Research Team · Updated June 2026
What is AOD-9604?
AOD-9604 is a synthetic peptide derived from the C-terminal region of human growth hormone, corresponding to residues 176-191, with a tyrosine substituted for the phenylalanine at the N-terminal position. It is a 16-amino-acid peptide (hexadecapeptide) and, in published studies, has been characterized as not binding the growth hormone receptor or inducing IGF-1 production. It is supplied strictly as a research-use-only compound and is not an approved drug; its name historically derives from the abbreviation ‘AOD’ used during early research.
How AOD-9604 is studied
In preclinical models, AOD-9604 has been studied in connection with adipose-tissue lipid metabolism, with research describing effects on lipolysis and lipogenesis signaling. Work in obese and beta-3 adrenergic receptor (beta3-AR) knockout mice (Heffernan et al., Endocrinology 2001) reported that the lipolytic activity observed in those models was associated with the beta-3 adrenergic receptor pathway rather than the classical growth hormone receptor. These are mechanistic observations from animal and in vitro research only and do not describe human outcomes.
Research areas
- Studied in rodent and in vitro models in the context of adipose-tissue lipid metabolism (lipolysis/lipogenesis signaling)
- Investigated in preclinical research on beta-3 adrenergic receptor (beta3-AR) dependent pathways
- Used as a reference C-terminal growth-hormone fragment to study receptor-independent metabolic activity (no GH-receptor binding / no IGF-1 induction reported in cited studies)
- Subject of analytical and anti-doping detection method development (e.g., mass spectrometry assays)
- Explored in exploratory preclinical work on metabolic research questions
These describe laboratory/preclinical research only. No therapeutic, medical, or efficacy claims are made.
AOD-9604 specifications
Handling & quality
AOD-9604 is held to a ≥ 99% HPLC purity standard with a Certificate of Analysis available per batch. Reconstitute with bacteriostatic water and store refrigerated; handle strictly for research. See reconstitution & storage.
Frequently asked questions
What is AOD-9604?
AOD-9604 is a synthetic peptide derived from the C-terminal region of human growth hormone, corresponding to residues 176-191, with a tyrosine substituted for the phenylalanine at the N-terminal position. It is a 16-amino-acid peptide (hexadecapeptide) and, in published studies, has been characterized as not binding the growth hormone receptor or inducing IGF-1 production. It is supplied strictly as a research-use-only compound and is not an approved drug; its name historically derives from the abbreviation ‘AOD’ used during early research.
Is AOD-9604 research use only?
Yes. AOD-9604 is supplied strictly for laboratory research — not for human or veterinary use, and not as a drug, food, or supplement.
Does Banger Labs provide a COA for AOD-9604?
Yes — a Certificate of Analysis (HPLC purity + mass-spec identity) is available per batch on request. See the COA Library.
References
- The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice — PubMed (Endocrinology, 2001; PMID 11713213)
- AOD9604 — Wikipedia (overview with primary-source references)
Sources are provided for scientific reference and describe laboratory/preclinical research; they do not constitute medical advice or efficacy claims.
Shop AOD-9604 & related research peptides
By the Banger Labs Research Team. For research use only. Not for human or veterinary use. Not a drug, food, or cosmetic. Educational information, not medical advice.